BMT-73107 Bioceramics and their Clinical Applications, 5 cr

Person responsible

Jonathan Massera


Implementation Period Person responsible Requirements
BMT-73107 2019-01 2 Jonathan Massera
Pass the exam (grade at leats 1) AND present the group work/report

Learning Outcomes

1. Students understands the tissue-implant interaction and can apply their knowledge to case study 2. Students can evaluate the appropriateness of a given bioceramics to a specific application 3. Students can differentiate ceramics bioactivity based on the understanding of surface chemistry 4. Students can analyze research data and disseminate knowledge to their fellow students on a topic of their choice 5. Students can weigh the benefit and inconvenience of implants from a clinical, manufacturing, processability point of view


Content Core content Complementary knowledge Specialist knowledge
1. The structure and mechanical properties of bioceramics.   The effect of crystalline and amorphous structures on the bioceramics bioactivity. The limitations of bioceramics mechanical properties in their possible clinical applications.  How to control the bioactivity of bioceramics. 
2. Biological interactions of bioceramics with the body.  How the bioactivity of certain glasses is based on the basic chemistry and reaction pathways.   How different locations in the body affect the chemistry of bioactive glasses. Differences in chemistry of different bioactive glass products; monoliths, fibers, porous materials, fine powders, etc.  
3. Fabrication of bioceramics.   The factors that have to be considered when manufacturing bioactive ceramic coatings or bioactive glasses.   The benefits and problems of melt derived bioactive glasses and sol-gel derived bioactive glasses. 
4. Analysis methods of bioceramics.   The chemistry of bioactive ceramics in in vitro studies. The composition of simulated body fluid.  The limitations of bioactive ceramics in "in vitro" studying compared to "in vivo" studying. The formation of bond between bioactive ceramic and host bone.  
5. Examples of different types of bioceramics and their clinical applications.   Different bioactive ceramics classifications based on their bioactivity.   Why bioactive glasses show bioactivity? The meaning of Silica in bioactive ceramics. 
6. Bioceramics in dental implant  action of bioceramics on teeth sensitivity and fluoroapatite formation  how bioactive glass can regenrate enamel? 
7. Bioceramics in cancer treatment  Biocermics as drug delivery system. Bioceramics can be tailored to favor cancer prognosis  Bioceramics and radiotherapy 

Instructions for students on how to achieve the learning outcomes

The final grade of the course is determined based on the assessment of all part of the course. The weighting factor of each part is given at the beginning of the course. Grades 1-2: Learning outcomes have been achieved. Satisfactory command in core content of the course. Grades 3-4: Some learning outcomes have been exceeded qualitatively or quantitatively. Good command in core content and complementary knowledge of the course. Good or very good marks from all parts of the course. Grade 5: Most of the learning outcomes have been exceeded. Deep command in the whole content of the course. Almost maximum performance in all parts of the course.

Assessment scale:

Numerical evaluation scale (0-5)

Partial passing:

Completion parts must belong to the same implementation

Study material

Type Name Author ISBN URL Additional information Examination material
Book   Bio-Glasses: An Introduction   Julian R. Jones, Alexis G. Clare   9780470711613       No   
Book   Bioceramics and Their Clinical Applications   Tadashi Kokubo   9781845694227       No   


Course Mandatory/Advisable Description
BMT-61227 Medical Biomaterials Mandatory    

Correspondence of content

Course Corresponds course  Description 
BMT-73107 Bioceramics and their Clinical Applications, 5 cr BMT-73106 Bioceramics and Their Clinical Applications, 4 cr  

Updated by: Kunnari Jaana, 05.03.2019