BMT-7816 Biosensors, 5 cr

Additional information

Suitable for postgraduate studies.

Person responsible

Sampo Tuukkanen, Jukka Lekkala, Antti Vehkaoja

Lessons

Implementation Period Person responsible Requirements
BMT-7816 2019-01 3 - 4 Sampo Tuukkanen
Antti Vehkaoja
Passed exercises, laboratory work and examination.

Learning Outcomes

After successful completion of the course the student will understand the physical operating principles of biosensors. He/she knows the basic terms and definitions. He/she understand the biology of the sensing elements and specific molecular recognition principles. The student is able to give examples of different biosensor structures and is able to understand and analyse measurement circuits and amplifiers that have been used with them. The student can model and simulate the function of simple biosensors. He/she understands the limitations of the sensors. The student can list different biosensors and of their application areas.

Content

Content Core content Complementary knowledge Specialist knowledge
1. Applications and requirements of biosensors.   Definition of concentrations, sampling principles    
2. Principles of molecular recognition, structure of enzyme and antibody, immunosensors, modeling of reactions, immobilization techniques.   Immune response, bacteria and viruses, self-assembled membranes   Molecular modeling, Langmuir-Blodgett -thin film technology  
3. Detection methods, electrodes, ISFET, optical sensors, Surface Plasmon Resonance (SPR) sensor, piezoelectric resonators and thermal sensors.   Principles of electrochemistry, operation principles of optical fibre sensors, modeling of SPR sensor.    
4. Miniaturization, biocompatibility, microanalyzers and BioMEMS structures.   Biomaterials, Micro ElectroMechanical systems (MEMS)   
5. Examples of commercial biosensors.      

Instructions for students on how to achieve the learning outcomes

The grade of the course is determined by examination. If the student knows the core material well, there is a possibility to pass the course with grade 3. The supplementing knowledge must be also known in order to reach a grade of 4 or 5. If in the core material there are minor shortcomings, the student will have an opportunity for the grade 1 or 2 depending on the amount of the shortcomings. Activity in exercises gives the opportunity for the additional points in the examination. If there are considerable shortcomings in the knowledge of the core material, the student will not pass the course.

Assessment scale:

Numerical evaluation scale (0-5)

Partial passing:

Completion parts must belong to the same implementation

Study material

Type Name Author ISBN URL Additional information Examination material
Book   Biomolecular sensors   Gizeli and Lowe   0-7484-0791-X       Yes   
Book   Engineering Biosensors - Kinetics and Design Applications   Ajit Sadana   0-12-613763-3     Chapters 2 & 3   Yes   
Lecture slides   Biosensors   Jukka Lekkala         Yes   

Prerequisites

Course Mandatory/Advisable Description
BMT-3036 Microsensors Advisable    

Additional information about prerequisites
Chemistry and biochemistry studies help understanding the biological part of biosensors. The english courses are for international students.



Correspondence of content

Course Corresponds course  Description 
BMT-7816 Biosensors, 5 cr ASE-7816 Biosensors, 5 cr  

Updated by: Kunnari Jaana, 05.03.2019