BMT-72106 Cellular Biophysics , 5 cr

Person responsible

Soile Nymark

Lessons

Implementation Period Person responsible Requirements
BMT-72106 2019-01 4 Soile Nymark
Accepted assignments, excercises, and final exam.

Learning Outcomes

Student can explain the principles of cellular electrophysiology and mechanobiology, and their measurement techniques. Student understands the fundamentals of biomechanics of the extracellular environment (extracellular matrix: its components), cellular mechanics (force generation and force sensing), electrophysiological properties of cells and tissues as well as the relevant cellular components (ion channels, transporters). Student can analyze, calculate and model mechanobiological and electrophysiological phenomena at the cellular level.

Content

Content Core content Complementary knowledge Specialist knowledge
1. Extracellular matrix components  Cell attachement to the extracellular matrix  Extracellular matrix biomechanics 
2. Force generation in the cells  Cellular components that are involved in the process  How forces are transduced within the cells 
3. Force sensing in the cells  Cellular components that are involved in the process  How forces are sensed in the multicellular level 
4. Electrophysiological properties of cells and tissues  Cellular components involved in the electrophysiological phenomena  Electrophysiological measurement techniques 
5. Electrical signaling in the cell and between the cells  Electrical signal propagation in tissues  Measurement of electrical cell-cell signaling 

Instructions for students on how to achieve the learning outcomes

The final grade of the course is determined based on the assessment of all parts of the course. The weighting factors are: exam 66%, project works 33%, exercises up to 3 bonus points. 1: The student understands the basics of mechanobiology and electrophysiology. 3: Student can explain the basic principles of cellular electrophysiology, mechanobiology, and their measurement techniques, and describe the relevant cellular components. Student can utilize this knowledge in calculations of biophysical phenomena. 5: In addition to grade 3 requirements, student is able to apply the new knowledge and solve problems in cellular biophysics.

Assessment scale:

Numerical evaluation scale (0-5)

Partial passing:

Completion parts must belong to the same implementation

Study material

Type Name Author ISBN URL Additional information Examination material
Lecture slides   Lecture slides           Yes   

Prerequisites

Course Mandatory/Advisable Description
BMT-51016 Introduction to Cell and Molecular Biology Mandatory    



Correspondence of content

Course Corresponds course  Description 
BMT-72106 Cellular Biophysics , 5 cr ELT-72106 Cellular Interactions, 5 cr  

Updated by: Kunnari Jaana, 05.03.2019