Computational Biophysics and Imaging Group (CBIG)
We at CBIG drive to deliver new knowledge and methods for future personalized medicine. We are interested in understanding and assessing mechanisms of cellular biophysics by developing in-vitro, 3D bioimaging and computational modelling tools for assessing the cellular functions.
- We study the cellular biophysics, especially electrophysiology and biomechanics using and developing microscopy, bioimpedance, patch clamp, and multichannel electrode arrays (MEAs). Our close collaborator, PhD Soile Nymark's research group Biophysics of the Eye is concentrating on this area.
- We develop new methods for 3D bioimaging and image-based assessment of cellular and tissue functions developing multimodal and hybrid imaging systems with optical, electric and X-ray 3D imaging methods
- We develop computational models to decipher the cellular biophysics integrating in-silico and in-vitro human induced stem cell personalized and drug screening platforms.
Main Research Topics and Expertise
- Cellular Biophysics: From electrophysiology to mechanobiology
- Bioimaging: Tomographic 3D imaging and analysis
- Computational Modelling: Simulations of cardiac and epithelial cells as well as neuronal-astrocytic networks