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Computational models shed light on Alzheimer’s disease

The doctoral dissertation of MSc (Tech) Eeva Toivari explores computational models that are built to simulate the plasticity of the human brain at the molecular level. The models are used to collect information that increases our understanding of Alzheimer’s disease.

Neuroscientific research generates a wealth of data on the human brain, such as the mechanisms underlying brain plasticity. The findings help researchers in their efforts to build a comprehensive theory of how the brain works.

Toivari’s dissertation focuses on modelling disturbances in calcium signalling in the brain. 

“Calcium regulates a wide range of vital cell functions and sustained dysregulation of intracellular calcium signalling has been associated with chronic diseases, such as Alzheimer’s,” says Toivari.  

Public defence of a doctoral dissertation on Friday, 1 February

The doctoral dissertation of MSc (Tech) Eeva Toivari in the field of computational neuroscience titled “Evaluation of simulation tools and modeling of calcium signaling in brain cells” will be publicly examined at the Faculty of Computing and Electrical Engineering of Tampere University of Technology (TUT) in room TB109 in the Tietotalo building (address: Korkeakoulunkatu 1, Tampere, Finland), at 12:00 on Friday, 1 February 2013.

The opponent will be Associate Professor Aušra Saudargiené (Vytautas Magnus University, Kaunas, Lithuania). Adjunct Professor Marja-Leena Linne from the Department of Signal Processing at TUT will act as Chairwoman.

Eeva Toivari (32) comes from Pirkkala, Finland, and works as a chemist at Satakunta Central Hospital. 

Further information:
Eeva Toivari, tel. +358 50 348 0863, firstname.lastname@satadiag.fi

 

News submitted by: Naukkarinen Anna
Keywords: science and research, image and communications, doctoral dissertation