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Battery-less implants enable continuous monitoring of physiological parameters

Implantable passive LC-based sensors can enable the wireless measurement of physiological parameters in inaccessible locations of the human body through RF telemetry links. In his doctoral dissertation, Mohammad Behfar developed a wireless platform for continuous wireless ICP monitoring.

Implantable passive LC-based sensors are intended to provide long-term continuous measurement of a desired parameter in patients with chronic diseases without the need for an implanted battery. The passive sensors are considered promissing altenatives to the existing cathere-based transducers and can be used in a variety of applications, including intraocluar pressure (IOP) monitoing, intracranial pressure (ICP) monitoing, and caradiovascular pressure sensing.

Considerable research has been conducted in the past few decades to develop clinically approved passive pressure sensors for real-life biomedical applications. The key challenge in the measurement with the LC-based sensors is the long-term drift when implanted in vivo. Moreover, the clinical utilization of this type of sensors requires a dedicated external reader device to communicate with the implant for ICP readout.

In the WISE Lab at Tamepre University of Technology (TUT), doctoral student Mohammad Behfar has developed a wireless platform for continuous wireless ICP monitoring as a part of his doctoral studies. The biotelemetry system includes an implantable sensor, which communicates with an external hand-held reader device. The proposed system also includes a dedicated PC application for real-time monitoring and assessment of the ICP data. In his dissertation, Behfar proposes a practical solution for tackling the classic challenge of the long-term drift of the LC-based sensors.

“The results can potentially be a step toward a clinical trial and the establishment of an inexpensive and efficient method for long-term wireless ICP monitoring. Considering their lifesaving impacts on the target group, the sensors hold huge potential for commercialization and thereby open up opportunities for establishing local healthcare startup companies to bring the clinically approved prototypes to the biomedical market,” Behfar says.

Public defense of a doctoral dissertation on Friday, 9 February 2018

M.Sc. Mohammadhossein Behfar will publicly defend his doctoral dissertation titled ‘Design, Development and in vivo Evaluation of a Wireless Platform for lntracranial Pressure Monitoring Using Inductive Passive Implants’ in the Faculty of Biomedical Sciences and Engineering at Tampere University of Technology in room SA203 in the Sähkötalo building (address: Korkeakoulunkatu 3, Tampere, Finland) on Friday, 9 February 2018 starting at 12.00.

Professor Smail Tedjini (Grenoble Institute of Technology, France) will act as the opponent. The Custos is Professor Leena Ukkonen (Biomedical Sciences and Engineering, TUT).

The dissertation is available online at http://urn.fi/URN:ISBN:978-952-15-4092-9

Further information: Mohammadhossein Behfar, tel. +358 40 0551690,

News submitted by: Sanna Kähkönen
Keywords: science and research, biomedical sciences and engineering